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Of all dogs diagnosed to have Exocrine Pancreatic Insufficiency (EPI), the German Shepherd is a common patient as well as the Roughcoated Collie One estimate shows that about 70% of all dogs diagnosed with Exocrine Pancreatic Insufficiency (EPI) are German Shepherds while % diagnosed are Roughcoated Collies Exocrine pancreatic insufficiency (also called EPI) is aExocrine Pancreatic Insufficiency (EPI) is the inability of the acinar cells of the exocrine pancreas to produce and secrete the 3 necessary enzymes needed to digest food In easy terms the pancreas stops producing the enzymes needed to absorb the goodness from food The three enzymes are Amylase for digestion of carbohydrates (sugars and starches in grains, fruits & vegetables)Exocrine pancreatic insufficiency (also called EPI in the GSD) is a medical condition in which the pancreas stops producing enough digestive enzymes to digest food normally in the small intestine In dogs diagnosed to have Exocrine pancreatic insufficie...